Among assets belonging to Vincenzo Graziano was a Ferrari, BMW and a 20-metre luxury yacht.
Investigators say the assets were the fruit of money-laundering activities.
Graziano is considered "a prominent part of the Acquasanta mafia family," according to investigators.
The seizures included companies and real estate.
Mafia watchers contend that organized crime organisations reap tens-of billions-of-euros through public sector contracts, drug trafficking, prostitution and other activities.
Italian interior minister Roberto Maroni in November said that 28 of the country's 30 most wanted mafia bosses have been arrested since the conservative government led by prime minister Silvio Berlusconi came to power in the Spring of 2008. During that period 35 thousand suspected mafia assets valued at 18 billion euros were seized, according to Maroni.